2022 MOZAFFARIAN
Effectiveness of a Novel Omega-3 Krill Oil Agent in Patients with Severe Hypertriglyceridemia, a Randomized Clinical Trial
Published randomized, double-blind, placebo-controlled
Location: USA, CAN, MEX |
Time Frame: 26 wks |
Population: Subjects with hypertriglyceridemia
Age Range: 18+ |
Total Subjects: 520 |
Krill Oil Group: n=372 |
Dose: 4/g/day of krill oil (885 mg EPS, 345 mg DHA) |
Placebo Gourp: n=148 |
Dose: 4/g/day of krill oil (885 mg EPS, 345 mg DHA) |
Key Significant Krill Oil Results vs Placebo:
- Reduced TG levels by 26% at 12 wks (p=.02) and 33.5% at 26 wks (p=.02)
- Increased percentage of subjects to achieve TG levels <500 mgs (p=.02)
- Reduced non-HDL at 26 wks (p=,04)
- Reduced ApoC3 at 26 wks (p=.03)
- Increased EPA/DHA at all study visits (p<.05)
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See Jounal Article
2018 RUNDBLAD
Effects of krill oil and lean and fatty fish on cardiovascular risk markers: a randomized controlled trial
Published randomized, double-blind, placebo-controlled
Location: Norway |
Time Frame: 8 wks |
Population: Healthy subjects
Age Range: 18-70 |
Total Subjects: 36 |
Krill Oil Group: n=12 |
Dose: 4/g/day of krill oil (885 mg EPS, 345 mg DHA) |
Fish Group: n=12 |
Dose: 3 weekly fish meals (245 g lean/fatty fish) |
Placebo Group: n=12 |
Dose: 4/g/day of krill oil (885 mg EPS, 345 mg DHA) |
Key Significant Krill Oil Results vs Placebo:
- Reduced in fasting glucose levels (p=.01)vs fish and placebo
- Increased XS-VLDL vs fish and placebo (p=.007)
- Increased in EPA & DPA vs fish and placebo (p<.05)
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See Jounal Article
2016 CICERIO
Lipid-lowering and anti-inflammatory effects of omega 3 ethyl esters and krill oil: a randomized, cross-over, clinical trial
Published randomized, double-blind, placebo-controlled
Location: Italy |
Time Frame: 16 wks |
Population: Subjects with hypertriglyceridemia
Range: 18-70 |
Total Subjects: 25 |
Krill Oil Group: n=25 |
Dose: 1/g/day of krill oil (150 mg EPS, 90mg DHA) |
Placebo Gourp: n=25 |
Dose: 2/g/day of fish oil EE (85% EPA/DHA) |
Key Significant Krill Oil Results vs Placebo:
- Improved HDL-C and apoAI levels vs baseline and Fish oil (p<.05)
- Improved non HDL cholesterol vs Fish oil (p<.05)
- More efficaciously improved hs-CRP levels vs placebo (p<.05)
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See Jounal Article